►个人简介

工作职位：副教授，硕士生导师

办公地址：青岛科技大学CCF大楼1121

工作邮箱：caoguorui@qust.edu.cn

2016年毕业于青岛科技大学化学工程与技术专业，获博士学位。主要研究方向为药物中间体及精细化学品合成工艺开发，发表科研论文20余篇，授权发明专利3项，主持企业委托横向项目3项。

►教学情况

1、本科生课程

[1] 化工制图：32学时，本科生，约120人。

[2] 化工制图上机：16学时，本科生，约120人。

►论文、专著与专利

1、主要论文

[1] Wenqing Hao, Long Wang, Jinlei Zhang, Dawei Teng and Guorui Cao*,Synthesis of spiropyridazine-benzosultams by the [4 + 2] annulation reaction of 3-substituted benzoisothiazole 1,1-dioxides with 1,2-diaza-1,3-dienes，Beilstein J. Org. Chem. 2024, 20, 280–286

[2] Ting Ma , Guorui Cao*, Recent developments in the synthesis of spirobenzosultams，Chemistry of Heterocyclic Compounds 2023, 59, 246–248

[3] Yangyang Hao, Xianzhao Wang, Mingzhe Zhu, Xiafei Jiang, Long Wang, Guorui Cao*, Shuping Pang  and Zhongmin Zhou*，Sulfonyl passivation through synergistic hydrogen bonding and coordination interactions for efficient and stable perovskite solar cells，J. Mater. Chem. A, 2022, 10, 13048–13054

[4] Luzhen Jiao, Dawei Teng, Zixuan Wang and Guorui Cao*，Silver Catalyzed Site-Selective C(sp3 )−H Bond Amination of Secondary over Primary C(sp3 )−H Bonds，Molecules 2022, 27, 6174

[5] Rui Sun, Zhongxuan Qiu, Guorui Cao, Dawei Teng*，Ni(II)/tBu-SMI-PHOX catalyzed enantioselective addition of arylboronic acids to cyclic N-sulfonyl aldimines，Tetrahedron 76 (2020) 131201

[6] Guorui Cao, Xiang Liu, Long Wang, Yanshun Li, Dawei Teng*，Cascade 1,3-dipolar Cycloaddition/SO2 extrusion approach for the rapid synthesis of tetraaryl-substituted pyrazoles with Aggregation Induced Emission characteristics，Tetrahedron 76 (2020) 131568

[7] Guorui Cao, Shizheng Zhou, Dawei Teng*，Synthesis of spiroisoxazolidinyl-benzoisothiazolines by 1,3-dipolar cycloaddition of benzoisothiazole-2,2-dioxide-3-ylidenes with nitrones， Tetrahedron 73 (2017) 2329-2333

[8] Guorui Cao , Kun Yang , Yue Li , Longjiang Huang and Dawei Teng*，Synthetic Strategy and Anti-Tumor Activities of Macrocyclic Scaffolds Based on 4-Hydroxyproline，Molecules 2016, 21, 212

[9] Guorui Cao, Yu Wang, Tao Cui, Longjiang Huang and Dawei Teng*，Synthesis of 3,4,5-trisubstituted isoxazoles via 1,3- dipolar cycloaddition/SO2 extrusion of benzoisothiazole-2,2-dioxide-3-ylidenes with nitrile oxides，RSC Adv., 2016, 6, 22519–22525

[10] Guorui Cao, Feifei Long, Yingchun Zhao, Yu Wang, Longjiang Huang, Dawei Teng*, Synthesis of spiropyrrolidinyl-benzoisothiazoline derivatives by 1,3-dipolar cycloaddtion of benzoisothiazole-2,2-dioxide-3-ylidenes and azomethine ylide, Tetrahedron, 2014, 70, 9359–9365.

2、授权专利

[1] 曹国锐;王龙;滕大为;龙中柱;蔡畅;蔡水洪, 一种吡嗪螺苯并磺内酰胺化合物化合物及其合成方法与用途，ZL 202211373075.5

[2] 曹国锐；矫鲁振；李延顺；高楠星；滕大为， 一种制备1,3,4,5-四芳基取代吡唑的方法, ZL 201810922123. 9

►承担科研项目情况

[1] 广谱生物技术有限公司，横向项目120万， 项目负责人；

[2] 昌邑泰和新材料科技有限公司，横向项目60万，项目负责人；

[3] 青岛和兴精细化学有限公司，横向项目30万，项目负责人；

[4] 公安部物证鉴定中心，开放课题2万，项目负责人。